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. 2006 Nov;128(5):593–604. doi: 10.1085/jgp.200609648

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Copyright © 2006, The Rockefeller University Press

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Figure 7. — Reducing endogenous PI(4,5)P₂ levels shifts HCN2 activation to more negative voltages. (A) Time course of V_1/2 in a single inside-out patch experiment in response to bath application of 30.3 μg/ml of anti-PI(4,5)P₂ antibody. (B) Time course of average V_1/2 shifts after bath application of anti-PI(4,5)P₂ antibody (squares) or heat-inactivated antibody (inverted triangles).