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. 2007 Mar;129(3):221–231. doi: 10.1085/jgp.200609658

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Copyright © 2007, The Rockefeller University Press

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Figure 2. — Estimation of the unitary LDCV capacitance increase. (A) P₂X₂ receptor–mediated TICs (top) and increase in whole-cell capacitance (bottom) recorded simultaneously in the same cell. Exocytosis was elicited by inclusion of 230 nM free Ca²⁺ in the pipette solution. Each segment (5 s) was preceded by a brief prepulse with a sine wave to measure the cell capacitance. (B) Plot of the cumulative number (ΣN) of purinergic TICs vs. membrane capacitance (C_m) from the same experiment. A linear fit (dotted line) with a slope of 3.18 fF/event is superimposed.