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. 2007 Mar;129(3):209–220. doi: 10.1085/jgp.200609662

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Copyright © 2007, The Rockefeller University Press

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Figure 1. — The S0 segment and its sequence conservation across BK channel orthologues. (A) Topology of the BK channel subunit; the S0 segment is shaded gray. (B) Alignment of nonidentical slo1 and mammalian slo3 S0 segments. Residues shaded black are 100% identical among all slo1 and slo3 sequences; residues shaded gray are 100% identical among all slo1 sequences. Residues in bold (F34, F38, I39 in mslo1) were the most variable among slo1 sequences. Accession nos.: mouse slo1, NP_034740; fly slo1, Q03720; cockroach slo1, AAN76819; mosquito slo1, AAL40812; C. elegans (nematode) slo1, Q95V25; mouse slo3, AAB99742; chimpanzee slo3, XP_519704.