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. 2007 Apr;129(4):345–350. doi: 10.1085/jgp.200709757

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Copyright © 2007, The Rockefeller University Press

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Figure 5. — Residues adjacent to E79C differ in their apparent state dependency of modification. (A and B) Representative traces from cells transfected with either D78C (left) or R80C (right) without and with (arrows) exposure to 1 mM MTSES for 5 min at pH 8.0 (A) or pH 6.0 (B). (C) Average time constants for desensitization. NA indicates no application of MTSES. A minimum of five cells was tested for each condition. D78C channels failed the statistical test for being modified by MTSES, whereas R80C channels are modified at both pH 6.0 and pH 8.0 (* indicates P < 0.001 vs. WT cells).