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. 2007 Jun;129(6):493–508. doi: 10.1085/jgp.200609604

Figure 5.

Figure 5.

Ca2+ influx during train stimulation is higher in GK rat β cells. (A) Depolarization train–evoked change in [Ca2+]i in (i) a Wistar and (ii) a GK rat β-cell measured by ratiometric imaging of cells loaded with 50 μM Fura-PE3. (B, i) Average Ca2+ influx for each depolarization pulse in control (closed symbols, n = 33) and diabetic (open symbols, n = 20) β cells measured as integrated Ca2+ current. (ii) Same as in i but normalized to the cell size (unpaired t test).