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. 2007 Oct;130(4):335–349. doi: 10.1085/jgp.200709759

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Copyright © 2007, The Rockefeller University Press

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Figure 5. — Parameter values for the five-state gating model. Values for the five-state model parameters were derived for both the dataset published by Chen and Miller in 1996 (CM) and for the dataset we obtained using macroscopic recordings (EM). In both cases, parameter values were derived by globally fitting the opening rate constant as a function of voltage and external chloride (α(V, [Cl]_ext)) (Method 2) (fits shown in Fig. 2, A and B), either with all six parameters free (free) or while holding z _c at 0.08 (held) (see the supplemental material for explanation, and Figs. 3 and S4, subset of voltages). The error bars show the 95% confidence limits determined as described in the text. For comparison, the first column shows the parameter values published by Chen and Miller (*).