TABLE III.
Interdependence of Parameters
| Four-state model | |||||
|---|---|---|---|---|---|
| z1 * | α2 * | z2 * | Kc(0) | z c | |
| α1 * | + | – | – | – | – |
| z1 * | – | – | – | – | |
| α2 * | ++ | ++ | + | ||
| z2 * | ++ | ++ | |||
| Kc(0) | + | ||||
| Five-state model | |||||
| z1 | γ | zγ | Kc(0) | z c | |
| α1 | ++ | – | – | – | – |
| z1 | – | – | – | – | |
| γ | + | ++ | + | ||
| zγ | + | ++ | |||
| Kc(0) | + |
Contour plots such as those shown in Fig. S6 were used to judge the interdependence of pairs of parameters when α(V, [Cl]ext) is globally fit (using Method 2) to the four- and five-state models. + indicates interdependence, ++ indicates strong interdependence, – indicates no interdependence.