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. 2007 Dec;130(6):631–645. doi: 10.1085/jgp.200709859

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Copyright © 2007, The Rockefeller University Press

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Figure 1. — Single InsP₃R channel current traces showing long-term modal gating behavior. Current records were obtained with [InsP₃] = 10 μM (saturating), and [Ca²⁺]_i = (A) 100 nM, (B) 1 μM, and (C) 89 μM. A continuous current record is shown for each condition. The arrows on the left indicate the closed-channel background current levels for this and all subsequent current traces. In B and C, arrowheads indicate some transitions when the InsP₃R channel gating behavior changed discernibly.