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. 2007 Sep 1;57(542):723–731.

Table 2.

Numbers, types, and clinical relevance of medication recommendations from pharmacists to GPs.

Feedback in writing (% within category of clinical relevance) Case conferences (% within category of clinical relevance)
Type of recommendation Not clinically relevant Potentially clinically relevant Clinically relevant Not clinically relevant Potentially clinically relevant Clinically relevant Example of clinically relevant recommendation

Dose unsuitable for patients 1 (4.8) 51 (9.5) 62 (42.2) 0 73 (10.8) 42 (26.9) Use of more than 20 mg of temazepam daily

Medicines unsuitable for patients aged ≥75 years 2 (9.5) 18 (3.3) 35 (23.8) 0 14 (2.1) 64 (41.0) Use of glibenclamide, which can cause prolonged hypoglycaemia

Medicine not useful at al 7 (33.3) 27 (5.0) 17 (11.6) 4 (12.5) 32 (4.7) 15 (9.6) Use of meprobamate, for which safer alternatives are available

Prescribing omissions 4 (19.0) 29 (5.4) 16 (10.9) 5 (15.6) 43 (6.4) 18 (11.5) Omitting to prescribe osteoporosis prophylaxis for a patient using high doses of corticosteroids for a long period

Incorrect duration of therapy 2 (9.5) 10 (1.9) 7 (4.8) 0 6 (0.9) 3 (1.9) Prolonged use of hypnotics

Unnecessary therapeutic duplication 0 39 (7.3) 3 (2.0) 1 (3.1) 40 (5.9) 5 (3.2) Simultaneous use of different benzodiazepines

Form of medication unsuitable for older people 0 12 (2.2) 3 (2.0) 2 (6.3) 16 (2.4) 0 Use of immediate release nifedipine capsules

Suitable for the indication? 0 53 (9.9) 2 (1.4) 0 111 (16.4) 3 (1.9) Patient uses an oestrogen preparation regularly used for complaints caused by menopause

Adherence (too much or too little use) 1 (4.8) 57 (10.6) 1 (0.7) 1 (3.1) 74 (10.9) 2 (1.3) Patient uses more oxazepam than prescribed

Contraindication known 2 (9.5) 9 (1.7) 1 (0.7) 6 (18.8) 12 (1.8) 3 (1.9) Use of amiodarone by patient suffering from hypothyreosis

Drug-drug interaction known 1 (4.8) 60 (11.2) 0 0 60 (8.9) 0

Treatment of side effect of other medicine 0 84 (15.6) 0 2 (6.3) 77 (11.4) 0

Others 1 (4.8) 88 (16.4) 0 11 (34.4) 118 (17.5) 1 (0.6) Use of a combination of amlodipine and losartan for a patient with oedema. Stop amlodipine and increase losartan dosage


Total 21 (100) 537 (100) 147 (100) 32 (100) 676 (100) 156 (100)

Number of records per patient 0.06 1.53 0.42 0.08 1.75 0.40

Total number 705 864

Number of records per patient 2.01 2.23 P = 0.059, difference = 0.229, 95% CI = −0.467 to −0.009