Table 1.
LVHP-S | HVLP-S | HVLP-P | OA | NIR | C | p | |
n = 10 | n = 10 | n = 10 | n = 10 | n = 4 | n = 5 | ||
Median (25–75) | Median (25–75) | Median (25–75) | Median (25–75) | Median (25–75) | Median (25–75) | ||
Weight (kg) | 0.22 (0.025–0.23) |
0.26 (0.23–0.27) |
0.255 (0.23–0.28) |
0.245 (0.225–0.26) |
0.263 (0.22–0.293) |
0.255 (0.24–0.26) |
0.35 |
Saline (ml/kg) | 2.63 (2.2–3.3) |
2.3 (1.55–3.3) |
1.8 (1.1–4.0) |
1.43 (0.9–2.4) |
-- | -- | 0.20a |
VT(ml/kg) | 8.8 (8.5–10.1) |
18.2 (17.2–20.6) |
18.59 (13.5–24.6) |
-- | -- | -- | 0.82b |
PEEP (cm H2O) | 12.13 (12.03–12.16) |
5.27 (5.09–5.46) |
5.26 (5.07–5.39) |
-- | -- | -- | 0.85b |
PAW (cm H2O) | 24.97 (23.57–25.59) |
23.7 (22.94–23.86) |
23.22 (22.99–23.56) |
-- | -- | -- | 0.09c |
pH | 7.05 (7.05–7.10) |
7.51 7.46–7.55) |
7.50 (7.47–7.54) |
-- | -- | -- | -- |
pO2 (mmHg) | 178.9 (169.6–193.9) |
177.0 (131-8–226.4) |
158.4 (115.3–188.0) |
-- | -- | -- | -- |
pCO2 (mmHg) | 70.7 (64.2–90.1) |
11.9 (11.5–13.1) |
14.1 (12.0–17.3) |
-- | -- | -- | -- |
Results are expressed as median and interquartile range (25–75). aKruskal-Wallis test between LVHP-S, HVLP-S, HVLP-P, and OA; bMann-Whitney test between HVLP-S and HVLP-P; cKruskal-Wallis test between LVHP-S, HVLP-S, and HVLP-P. C, control group; HVLP-P, high volume-low positive end-expiratory pressure, prone; HVLP-S, high volume-low positive end-expiratory pressure, supine; LVHP-S, low volume-high positive end-expiratory pressure, supine; NIR, no injury, recruited; OA, oleic acid injury, no ventilation; PAW, peak airway pressure; pCO2, carbon dioxide partial pressure; PEEP, positive end-expiratory pressure; pO2, oxygen partial pressure; VT, tidal volume.