Table 3.

IL-1β mRNA expression (logIL1) and PMI (logPMI) sorted by lung region

	LVHP-S	HVLP-S	HVLP-P	OA	NIR	C
	n = 10	n = 10	n = 10	n = 10	n = 4	n = 5
	Mean (SD)	Mean (SD)	Mean (SD)	Mean (SD)	Mean (SD)	Mean (SD)
logIL1 nondependent	0.1262 (0.1117)	0.3102 (0.0807)	0.2479 (0.1472)	0.2804 (0.1129)	--	-1.4306 (0.1692)
logIL1 dependent	0.1166 (0.1674)	0.2078 (0.1079)	0.2784 (0.1748)	0.2657 (0.1758)	--	-1.4749 (0.0646)
logPMI nondependent	0.0363 (0.1349)	0.1518 (0.1345)	0.1725 (0.1255)	0.1721 (0.1273)	-0.738 (0.1359)	--
logPMI dependent	0.0291 (0.0848)	0.1545 (0.1286)	0.2347 (0.1272)	0.1372 (0.1287)	-0.7697 (0.1276)	--

Results are expressed as mean and standard deviation (SD). Post hoc analysis for IL-1β expression: significant differences found between groups: (i) C versus HVLP-P, C versus HVLP-S, C versus LVHP-S, and C versus OA, p < 0.001; (ii) LVHP-S versus HVLP-P, p = 0.014; (iii) LVHP-S versus HVLP-S, p = 0.019; (iv) LVHP-S versus OA, p = 0.007. Post hoc analysis for PMI: significant differences found between groups: (i) NIR versus HVLP-P, NIR versus HVLP-S, NIR versus LVHP-S, and NIR versus OA, p < 0.001; (ii) LVHP-S versus HVLP-P, p < 0.001; (iii) LVHP-S versus HVLP-S, p = 0.026; (iv) LVHP-S versus OA, p = 0.024. C, control group; HVLP-P, high volume-low positive end-expiratory pressure, prone; HVLP-S, high volume-low positive end-expiratory pressure, supine; IL-1β, interleukin-1-beta; logIL1: logarithmic transformation of the expression of IL-1β mRNA normalized by GAPDH mRNA; logPMI, logarithm of the polymorphonuclear infiltratrion index; LVHP-S, low volume-high positive end-expiratory pressure, supine; NIR, no injury, recruited; OA, oleic acid injury, no ventilation; PMI, polymorphonuclear infiltrate.