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. Author manuscript; available in PMC: 2008 Jun 6.
Published in final edited form as: Neuron. 2007 Dec 6;56(5):823–837. doi: 10.1016/j.neuron.2007.09.035

Figure 3. Cdk5 mediates CASK distribution in synaptosomes.

Figure 3

(a) Synaptosome preparations were made using adult wild-type mouse brains. (b) CASK IPs were made from synaptosome fractions. (c) RIPA lysates from forebrains of adult Cdk5 cKO mice or control littermates were subjected to IP. (d) Synaptosomal preparations were made using brains from adult Cdk5 cKO or control littermates. (e) Relative amounts of CASK or Synaptophysin in purified synaptosome fractions were determined by densitometry and analyzed by One-Way ANOVA. For CASK, * indicates p<0.05 when comparing LS1 fractions and p<0.01 when comparing LS2 fractions. ** indicates p<0.001 when comparing LP1 fractions. n=3 for both genotypes. AU indicates arbitrary units and ns not significant.