Table 1.
Number of amino acid differences between glucagon-like peptides
|
Xenopus glucagon-like sequences
|
|||||
|---|---|---|---|---|---|
| Glucagon | GLP-1A | GLP-1B | GLP-1C | GLP-2 | |
| Xenopus glucagon | 0 | 15 | 17 | 16 | 15 |
| Bullfrog glucagon | 1 | 16 | 17 | 16 | 16 |
| Amphiuma glucagon | 3 | 15 | 17 | 16 | 15 |
| Human glucagon | 0 | 15 | 17 | 16 | 15 |
| Xenopus GLP-1A | 15 | 0 | 10 | 11 | 15 |
| Xenopus GLP-1B | 17 | 10 | 0 | 6 | 18 |
| Xenopus GLP-1C | 16 | 11 | 6 | 0 | 17 |
| Bullfrog GLP-1 | 14 | 10 | 9 | 5 | 16 |
| Amphiuma GLP-1 | 18 | 16 | 16 | 16 | 20 |
| Human GLP-1 | 15 | 9 | 8 | 9 | 17 |
| Xenopus GLP-2 | 15 | 15 | 18 | 17 | 0 |
| Bullfrog GLP-2 | 14 | 15 | 18 | 17 | 8 |
| Amphiuma GLP-2 | 15 | 16 | 17 | 17 | 8 |
| Human GLP-2 | 18 | 16 | 19 | 19 | 17 |