Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Transcription factors downregulated in 3/3 human OA chondrocyte samples by IL-1β.
| Factor | Ratios* | Average Ratio | Standard Deviation | ||
|---|---|---|---|---|---|
| TR(DR-4) | 0.55 | 0.64 | 0.39 | 0.53 | 0.13 |
| Smad3/4 | 0.7 | 0.6 | 0.45 | 0.58 | 0.13 |
Nuclear extracts from human OA chondrocytes treated with IL-1β were screened against the TranSignal protein/DNA-binding array (Panomics, Redwood City, CA).
Ratios indicate the intensity of binding of samples treated with IL-1β divided by the intensity of binding of untreated samples.
