Table 1.
Task force criteria for diagnosis of ARVC (McKenna et al.)7 The diagnosis of ARVC would be fulfilled by the presence of 2 major, 1 major plus 2 minor, or 4 minor criteria from different groups.
| I. Global and/or regional dysfunction and structural alterations |
| Major |
| - Severe dilatation and reduction of right ventricular ejection fraction with no (or only mild) LV impairment |
| Minor |
| - Mild global right ventricular dilatation and/or ejection fraction reduction with normal left ventricle |
| - Mild segmental dilatation |
| - Regional right ventricular hypokinesia |
| II. Tissue characterisation of wall |
| Major |
| - Fibrofatty replacement of myocardium on endomyocardial biopsy |
| III. Repolarisation abnormalities |
| Minor |
| - Inverted T waves in right precordial leads (V2 and V3) in people aged >12 years, in absence of right bundle branch block |
| IV. Depolarisation/conduction abnormalities |
| Major |
| - Epsilon waves or localised prolongation (>110 ms) of the QRS complex in right precordial leads (V1 to V3) |
| Minor |
| - Late potentials on signal-averaged ECG |
| V. Arrhythmias |
| Minor |
| - Left bundle-branch block type ventricular tachycardia (sustained and nonsustained) by ECG, Holter, or exercise testing |
| - Frequent ventricular extrasystoles (>1000/24 hours) on Holter |
| VI. Family history |
| Major |
| - Familial disease confirmed at necropsy or surgery |
| Minor |
| - Family history of premature sudden death (<35 years) due to suspected right ventricular dysplasia. |
| - Familial history (clinical diagnosis based on present criteria) |