Table 1.
Mice | Inositol phosphates, dpm*
|
Ca2+, nM†
|
Superoxide, pmol/min | MAC-1, %‡ | ||
---|---|---|---|---|---|---|
− PTx | + PTx | − PTx | + PTx | |||
PLC β2 +/+ | 1,247 ± 94 | 137 ± 50 | 101 ± 15 | ND | 13.8 ± 2.1 | 100 |
PLC β2 −/− | 239 ± 89 | 120 ± 75 | 29 ± 4 | ND | 1.66 ± 0.5 | 25.2 ± 10.2 |
Data are shown as mean ± SEM. At least three independent experiments were performed. ND, not detected.
The basal level of inositol phosphates is 898 ± 110 dpm.
The resting Ca2+ concentration is 84.2 ± 8.9 nM.
Data are expressed as a percentage of the +/+ levels.