Table 6.

Lack of correlation between serum FR titer and inhibitory factor in posttreatment serum

	Patient 2		Patient 9		Patient 10
	FR titer	IFN-γ response	FR titer	IFN-γ response	FR titer	IFN-γ response
Pretreatment	3	1,100	50	3,340	1,000	1,825
Posttreatment	6	0	1,650	390	900	1,550

NOTE: Serum FR titers were determined using ELISA. FR levels varied between patients, with patient 2 having low amounts and patient 10 high amounts both before and after treatment. Patient 9 experienced an increase in FR levels over the course of treatment. There was no consistent correlation between FR levels and inhibition of IFN-γ response against IGROV-1 tumor cells.