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. 2007 Dec 12;1(3):e96. doi: 10.1371/journal.pntd.0000096

Table 3. Serotype specificity of antibodies induced in CD46-IFNAR mice after immunization with recombinant vectors.

DV1 DV2 DV3 DV4
Ab titera FRNT50b Ab titera FRNT50b Ab titera FRNT50b Ab titera FRNT50b
MV 3,000 160 <100 nd <100 nd <100 nd
MV-EDIII 3,000 160 <100 40 <100 40 <100 40
MV-EDIII-ectoM 300,000 10240 500 40 <100 20 <100 10
a

Determined by ELISA using plates coated with rEDIII from DV1, 2, 3 or 4 produced in E. coli (pooled heat-inactivated post-DV inoculation sera from experiment presented in Table 2).

b

FRNT50 is the highest serum dilution that reduced the number of DV focus-forming units (FFU) on Vero cells by at least 50%.