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. 2007 Dec 10;104(51):20368–20373. doi: 10.1073/pnas.0709989104

Fig. 2.

Fig. 2.

mig-14 acts in multiple tissues to regulate VPC fusion with hyp7. Rescue experiments were performed in a mig-14;arIs99 background. The transgenic marker used for all lines was myo-3p::mCherry. Each bar represents a single transgenic line. The black bars represent negative control lines in which a promoter drives expression of a mutated mig-14 cDNA that does not make functional protein. The gray bars represent experimental lines in which a promoter drives a wild-type mig-14 cDNA that encodes a functional protein. dpy-7p::mig-14cDNA was injected at 5 μg/ml (the first two gray bars) and 10 μg/ml (the third gray bar). Animals were scored for whether P4.p fuses directly with hyp7, and the results for each line were compared against the P4.p defect observed in mig-14;arIs99, which is represented by the horizontal black line. P values were calculated by using a z test to compare the proportion of abnormal animals in each group. ***, P < 0.001; **, P < 0.01. n ≥ 50 for all lines.