Fig. 1.

MCp recruitment to the lung is reduced in antigen-challenged CXCR2^−/− mice. (A) Total number of lung MCp per mouse from OVA-sensitized WT (black bars) and CXCR2^−/− (open bars) mice with and without aerosolized OVA challenges. Values are the mean ± SE from eight determinations in seven separate experiments. (B) Concentration of MCp (MCp per 10⁶ MNC) in the lungs of the same mice. (C) Number of lung MNC recovered per mouse in the same mice. The asterisk (*) indicates statistical significance (P < 0.05) as determined by a two-tailed Student's t test.