Fig. 3.

WT BM does not reconstitute MCp recruitment to the lung of sensitized, sublethally irradiated, antigen-challenged CXCR2^−/− mice. (A) Total number of lung MCp per mouse from sensitized, sublethally irradiated, antigen-challenged WT mice without BM reconstitution (black bar), from sensitized, sublethally irradiated, antigen-challenged WT mice reconstituted with WT BM (open bar) and from sensitized, sublethally irradiated, antigen-challenged CXCR2^−/− mice reconstituted with WT BM (gray bar). Values are the mean ± SE from six WT and seven CXCR2^−/− mice in three separate experiments, except for the no reconstitution control, which was done in two of the three experiments. (B) Concentration of MCp (MCp per 10⁶ MNC) in the lungs of the same mice. (C) Number of lung MNC recovered per mouse in the same mice. The asterisk (*) indicates statistical significance (P < 0.05) as determined by a two-tailed Student's t test.