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Akt interacts with calcineurin and PP2A in cardiomyocytes. (A and B) Coimmunoprecipitation showing interaction of Akt with calcineurin and PP2A catalytic subunits but not with PP1. Experiments were repeated at least two times with independent cell lysates. (C) Decreased association between calcineurin and Akt or PP2A and Akt in cardiomyocytes overexpressing caFoxO1 relative to that seen in cells overexpressing GFP.
