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In vitro cytotoxicity of splenic NK cells isolated from CD158b transgenic mice. Freshly isolated nonadherent splenocytes from CD158b transgenic (Tg CD158b) mice (L47 and L26 mouse lines) and nontransgenic littermate (non Tg) were tested for their ability to kill the indicated target cell lines in a standard 4-hr cytotoxicity assay. The following mice were used in this representative experiment: L47.21 (H-2k/b), L26.4 (H-2b/b), and L26.5 (H-2k/b).
