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CD158b transgenic mice are tolerant to graft of allogeneic bone marrow cells that express HLA-Cw3. Incorporation of 125IdUdr in donor marrow-derived cells in the spleen of irradiated recipients 6 days after bone marrow graft was used as an assay to determine the extent of donor cell proliferation. Results are expressed as mean cpm ± SEM of incorporated 125IdUdr obtained from three independent grafts.
