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. 1999 Jul 26;146(2):405–414. doi: 10.1083/jcb.146.2.405

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© 1999 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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Dose dependence of time courses of global Ca²⁺ spikes induced by caged IP₃ or ACh. (A and B) Semilog plots of the time-to-peak of Ca²⁺ spikes in the trigger zone versus concentration of IP₃ (A) or ACh (B). (C and D) Semilog plots of spike spread time versus concentration of IP₃ (C) or ACh (D). (E and F) Semilog plots of spike delay time versus concentration of IP₃ (E) or ACh (F). Correlation coefficients are 0.066 (P > 0.1), 0.45 (P < 0.001), 0.29 (P > 0.1), 0.63 (P < 0.001), 0.003 (P > 0.1), and 0.61 (P < 0.001) for A through F, respectively.