Table 1.
WT1 protein expression: Survey of immunostaining in normal and cancerous breast tissue
Tissue | WT1 Neg | WT1 Pos |
---|---|---|
Tumor | 15 | 6 |
Normal | 1 | 14 |
In 60% (9 of 15) of the tumors surveyed, WT1 immunostaining was absent in greater than 90% of the tumor cells (estimated by inspection). In the remaining 6 tumors, 50% or more of the tumor cells were estimated to be WT1-negative. Source of normal tissue: ducts and lobules with normal-appearing cellular architecture and nuclear morphology were often found in the vicinity of tumors and were used as controls (Normal).