Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Ganglioside metabolism in gangliosidosis fibroblasts. [3H]GM1 ganglioside was added to fibroblast cultures for 120 hr. The glycolipids then were extracted, analyzed by thin-layer chromatography and visualized on a Raytest/Fuji BAS 1000 phosphoimager. (Left to right) Hexb −/−, Hexa −/−, DKO (double knockout, both Hexa −/− and Hexb −/−), Gm2a −/−, and control (wild-type) embryonic fibroblasts. Cer, ceramide; FFA, free fatty acid; GlcCer, glucosylceramide; LacCer, lactosylceramide.
