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. 1997 Jul 22;94(15):8144–8149. doi: 10.1073/pnas.94.15.8144

Figure 6.

Figure 6

Protection from CH-11-induced apoptosis by Bcl-2 in asynchronous cultures of TS− cells. Cells were plated as described in the presence of dThd (20 μM) and were transduced with Ad-VC or Ad-Bcl-2 at an moi of 50 for 24 hr before dThd withdrawal and treatment with various concentrations of CH-11 (20–100 ng/ml). Following 72 hr of exposure to CH-11, antibody was removed, and clonogenic survival was determined after a further 11 days. Data represent the mean ± SD of three determinations at each CH-11 concentration.