TABLE 1.

SR release parameters

Parameter	Definition	Value
τr	Spark lifetime	30 ms
τa	NSR-JSR relaxation time	100 ms
gRyR	Release current strength	2.58 sparks cm2/mA
u	Release slope	11.3 ms−1
csr	Threshold for steep release function	90 μM/l cytosol
s	Release function parameter	(1-u)csr-50 μM/ms = 977 μM/ms
τd	Submembrane-myoplasm diffusion time constant	4 ms
τs	Dyadic junction-submembrane diffusion time constant	0.5 ms