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. 1997 Jul 22;94(15):8202–8207. doi: 10.1073/pnas.94.15.8202

Table 1.

Summary of the binding constants of the nAChR after cross-linking

nAChR Kd, nM Hill coefficient
Native 75 1.6
DMS-treated 50 1.0
Glutardialdehyde-treated 35 (high affinity) 2,000–5,000 (low affinity) 1.0 1.0
Glutardialdehyde and carbamoylcholine 45 1.0