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. 1997 Jul 22;94(15):8208–8213. doi: 10.1073/pnas.94.15.8208

Figure 2.

Figure 2

Complex formation between PS1 or PS2 and APP in CHO cells. CHO cells stably transfected with PS1 or PS2 were lysed and precipitated (IP) with the indicated PS1 or PS2 antibodies, followed by blotting (WB) with APP antibody 8E5. Lower arrowhead indicates the coprecipitating N-APP polypeptide [compare with the N- and N+O-glycosylated APP precipitated by APP antibody B5 (lane 1)]. IP with antibodies to either PS1 (X81; 4627) or PS2 (2972; PS2L) coprecipitates APP indistinguishably. Bands at 50 and 25 kDa are IgG heavy and light chains.