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. 1997 Jul 22;94(15):8226–8231. doi: 10.1073/pnas.94.15.8226

Table 1.

EC50 values for noradrenaline-induced contractions

Conditions EC50, μM
Rabbit anococcygeus muscle Human corpus cavernosum Rat anococcygeus muscle
Control 1.8  ± 0.3 56.1  ± 6.2 19.4  ± 1.9
During EFS >300* >300* 20.8  ± 1.2
During EFS +l-NOARG 1.7  ± 0.3 48.3  ± 2.7 19.6  ± 1.0

EC50 values for noradrenaline-induced contractions under control conditions, during EFS, and during EFS after l-NOARG (300 μM) treatment in tissues treated with guanethidine (10 μM). 

*

P < 0.001 vs. control value; n = 4 for each. Where values are >300 μM, the EC50 was considered to be 300 μM for statistical comparison.