Table 2.

IL-2R expression and IL-2 reactivity of B, CD8 T, and CD4 T lymphocytes from group 1 and group 2 patients

	Healthy donors	Group 1 patients	Group 2 patients
Clinical characteristics
Viral load, copies per ml		2  ×  105	<200*
CD4 T counts per mm3		303	310†
Treatment		1 or 2 RT inhibitors	2 RT inhibitors + 1 protease inhibitor
B lymphocytes
IL-2R expression‡	0.8/0.8/0.9	16/39/43	2/4/4
IL-2 reactivity§	3	25	11
CD8 T lymphocytes
IL-2R expression‡	3/14/9	43/67/51	19/26/12
IL-2 reactivity§	6	6	16
CD4 T lymphocytes
IL-2R expression‡	5/2/4	10/11/11	10/10/3
IL-2 reactivity§	4	4	10

^*In 18 of 27 patients viral burden became undetectable (<200 copies per ml) and in 9 of 27 patients decreased at <1,000 copies/ml. 

^†Initial CD4 T count mean of group 1 patients was 94 per mm³ before TCT. 

^‡Mean percent of positive cells for IL-2Rα/IL-2Rβ/IL-2Rγ, respectively. 

^§Mean percent of cells entering in S + G₂/M phase after in vitro IL-2 stimulation.