Figure 8.
NT-3 signaling of β-actin mRNA localization through cAMP. NT-3 stimulation of β-actin mRNA localization was reduced by kinase inhibitors. K252a (200 nM) or Rp-cAMP (50 μM) was added to the MEM for 1 h after a 5-h starvation. Forskolin and db-cAMP stimulated β-actin mRNA localization in a similar fashion to NT-3. *, P < 0.01 when NT-3/K252a at 10min and NT-3/Rp-cAMP at 10min were compared with NT-3 at 10min. #, P < 0.01 when NT-3/K252a at 2h and NT-3/Rp-cAMP at 2h were compared with NT-3 at 2h.