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. 1998 Sep 15;95(19):11383–11388. doi: 10.1073/pnas.95.19.11383

Figure 5.

Figure 5

Anti-MIF antibody protects mice from lethal toxic shock induced by TSST-1. BALB/c mice were injected i.p. with 200 μl of anti-MIF or nonimmune rabbit serum 2 hr before the i.p. injection of TSST-1 (1 mg/kg) and d-galactosamine (0.9 g/kg). Data points are from four independent experiments, each of which included 8 to 10 mice per treatment group. Survival was 54% (21 of 39) in mice treated with anti-MIF serum and 8% (3 of 38) in mice treated with nonimmune serum (P = 0.00004, two-tailed χ2 test).