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Pretreatment with m1-toxin does not inhibit the CCh-induced reduction of evoked EPSCs. (A) Single traces demonstrating that 1 μM CCh inhibits evoked EPSCs in both control and m1-toxin-treated slices. (B) Mean (±SEM) data showing that CCh produces a significant inhibition of evoked EPSCs in both control and m1-toxin-treated slices (∗, P < 0.05; n = 4 for each condition). P, pre-drug; C, 1 μM CCh; W, washout.
