Figure 2.

Deduced amino acid sequences of LDH-A for 12 species of notothenioid fishes. The top line provides the consensus sequence, a dash indicates identity with the consensus, and a dot indicates a deletion. The bottom line is the consensus sequence of LDH-A for six non-notothenioid teleost species [the killifish Fundulus heteroclitus (29), the goby G. mirabilis (2), the barracudas Sphyraena idiastes and S. lucasana (3), the eelpout Austrolycos depressiceps, and the lampfish Lampanyctus ritteri (P.A.F. and G.N.S., unpublished data)]. In the teleost consensus sequence, an asterisk indicates residues evenly divided among the species; in each case, one of the residue pairs agrees with the notothenioid consensus, and the substituted residue is chemically similar.