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. Author manuscript; available in PMC: 2009 Jan 1.
Published in final edited form as: Neurochem Res. 2007 Aug 17;33(1):134–149. doi: 10.1007/s11064-007-9426-6

Table 1.

Experimental groups and number of animals used for each experiment

Group No. Group Description Designation No. of animals studied Immuno-histochemistry Caspase-3 activity Western Blot Behavioral studies
1. Control animals with laminectomy and PBS injected Sham control 10+5* 4 3 3 10+5*
2. Spinal cord injured and untreated animals Injured 18+5* 7 5 6 18+5*
3. Spinal cord injured and hUCB transplantation HUCB treated 19+5* 7+5* 5 7 19+5*
4. Spinal cord injured and cyclosporine treated Cyclosporine treated 5* - - - 5*

Three animals died unexpectedly during the course of the experiment; two from group 2(died of hematuria), one from group 3 (died of hematuria). Early data from these animals were omitted from the analysis. Animals were sacrificed after 21d after SCI (i.e., 14 d after transplantation of hUCB).

*

Animals sacrificed after 6 weeks. In hUCB treated group 5 animals were used for immunohistochemistry studies on in vivo transdifferentiation of hUCB in the injured spinal cord after 5 weeks of grafting.