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. Author manuscript; available in PMC: 2008 Dec 6.
Published in final edited form as: Oncogene. 2007 Jun 25;26(55):7675–7683. doi: 10.1038/sj.onc.1210584

Figure 4. Antagonistic Fas-L antibodies block Ad-MMP-2-induced apoptosis.

Figure 4

A549 cells were incubated for 1h with 10μg/mL of antagonistic Fas-L antibody or non specific antibody before infection with 100MOI of Ad-SV and 100MOI of Ad-MMP-2. Forty-eight hours later, apoptosis was determined by (A) TUNEL staining. (B) Quantitation of TUNEL positive cells. The, bars indicate standard errors (±SE) from the mean of three separate experiments. (C) Immuno blot analysis for cleavage of caspase-8 and PARP, (D) Apoptosis was not antagonized with Non-specific antibody. Immuno blots are representative of three experiments.