Table 1.
Self-administration histories (mg/kg) prior to [11C]DASB PET studies
|
1Weekly MDMA Intake |
Total MDMA Intake |
2Months of SA | (−) Cocaine | |
|---|---|---|---|---|
| MDMA Group | ||||
| R-1361 | 22.2 | 107.46 | 6 | 118.33 |
| R-1496 | 6.2 | 138.44 | 18 | 69.75 |
| R-1498 | 6.8 | 96.63 | 8 | 80.01 |
| R-1499 | 3.9 | 141.74 | 16 | 0.2 |
| Mean (± SEM) | 121.07 (13.0) | 12 (3.4) | 67.07 (28.4) | |
|
1Weekly Cocaine Intake |
Total Cocaine Intake |
2Months of SA | (±) MDMA | |
| Cocaine Group | ||||
| R-1268 | 1.8 | 1028.79 | 10 | 0.00 |
| R-1326 | 1.83 | 537.27 | 12 | 129.55 |
| R-1346 | 24 | 645.3 | 5 | 40.61 |
| R-1427 | 2.19 | 759.04 | 14 | 0.00 |
| Mean (± SEM) | 742.60 (121.9) | 10.25 (2.2) | 42.54 (35.3) |
1
Weekly Intake (mg/kg) refers to drug intake over the 5 days before the PET study.
2
“Months of SA” refers to the number of months each subject had been exclusively self-administering either MDMA or cocaine.