TABLE 2.

Plasma concentrations of A-837093 following oral dosing of 5 mg/kg in rats, dogs, and monkeys

Animal	t1/2 (h)a	Cmax (μg/ml)b	Tmax (h)b,c	AUC (μg·h/ml)b	F (%)b,d
Rat	7.6	0.31 ± 0.13	4.2 ± 1.8	3.3 ± 0.5	62.7 ± 8.7
Dog	10.7	1.94 ± 0.39	0.4 ± 0.1	10.5 ± 1.4	89.3 ± 11.5
Monkey	1.9	0.52 ± 0.22	2.7 ± 0.7	1.5 ± 0.5	15.2 ± 4.9

^aValues are harmonic means.

^bValues are the means ± standard errors of the means of three animals each.

^cT_max, time to C_max.

^dF, bioavailability.