TABLE 2.
Final parameter estimates of the model for each of the PK-PD measures
| Parametera | AUC0-24/MIC ratio | Cmax/MIC ratio | %t>MIC |
|---|---|---|---|
| Emax | 0.97 | 0.83 | 1.00 |
| ED50 | 11.8 | 8.10 | 27.5 |
| E0 | 0.10 | 0.07 | 0.08 |
| Gamma | 7.03 | 10.0 | 10.0 |
Emax, maximum effect; E0, effect at time zero; gamma, Hill's constant.