TABLE 2.
Relationship between predictors of outcome and mortality at 28 days
| Patient dataa | No. of patient deaths/total n (%) | P value | OR | 95% CI | 
|---|---|---|---|---|
| Organism types | ||||
| E. coli | 7/33 (21.2) | 0.25b | 0.6 | 0.2-1.5 | 
| P. aeruginosa | 18/46 (39.1) | 0.10 | 1.8 | 0.9-3.7 | 
| Enterobacter spp. | 5/23 (21.7) | 0.38 | 0.6 | 0.2-1.8 | 
| Klebsiella spp. | 7/23 (30.4) | 0.92 | 1.05 | 0.4-2.7 | 
| Proteus spp. | 1/4 (25) | 0.84 | 0.8 | 0.08-7.8 | 
| Serratia spp. | 5/21 (23.8) | 0.54 | 0.7 | 0.3-2.1 | 
| All others | 2/7 (28.6) | 0.95 | 0.95 | 0.2-5.1 | 
| Polymicrobial | 7/19 (36.8) | 0.46 | 1.5 | 0.6-3.9 | 
| APACHE-II scores | ||||
| 3-19 | 12/85 (14.1) | |||
| 20-24 | 10/38 (26.3) | 0.11c | 2.2 | 0.8-5.6 | 
| 25-29 | 12/22 (54.5) | 0.0002 | 2.7 | 1.6-4.5 | 
| 30-53 | 12/16 (75) | <0.0001 | 2.6 | 1.7-4.0 | 
| Sources of bacteremia | ||||
| CVC | 1/14 (7.1) | 0.09d | 0.2 | 0.02-1.3 | 
| UTI | 5/26 (19.2) | 0.22 | 0.5 | 0.2-1.5 | 
| Pneumonia | 13/34 (38.2) | 0.22 | 1.6 | 0.8-3.6 | 
| Other | 2/9 (22.2) | 0.62 | 0.7 | 0.1-3.3 | 
| Unknown | 31/93 (33.3) | 0.24 | 1.5 | 0.8-2.8 | 
| Creatinine clearance rates | ||||
| >100 ml/min | 4/28 (14.3) | |||
| 60-100 ml/min | 7/41 (17.1) | 0.76e | 1.2 | 0.3-4.7 | 
| <60 ml/min | 21/57 (36.8) | 0.039 | 3.5 | 1.1-11.5 | 
| CVVHD | 12/18 (66.7) | 0.0007 | 12.0 | 2.8-50.8 | 
| HD | 7/30 (23.3) | 0.28 | 2.1 | 0.6-7.9 | 
| Immune status | ||||
| Competent | 16/60 (26.7) | |||
| Compromised | 36/116 (31) | 0.55f | 1.2 | 0.6-2.5 | 
| Ages | ||||
| ≤64 | 28/105 (26.7) | |||
| ≥65 | 24/71 (33.8) | 0.31g | 1.4 | 0.7-2.7 | 
| Modes of therapy | ||||
| Monotherapy | 21/73 (28.8) | |||
| Combination therapy | 31/102 (30.4) | 0.82h | 1.08 | 0.56-2.09 | 
Abbreviations: CVC, central venous catheter; UTI, urinary tract infection; CVVHD, continuous venovenous hemodialysis; HD, hemodialysis.
P value compared to that of all other organisms.
P value compared to that of score range 3-19.
P value compared to that of all other sources.
P value compared to that of creatinine clearance of >100 ml/min.
P value compared to competent status.
P value compared to those aged ≤64.
P value compared to that of monotherapy.