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. 2007 Oct 15;51(12):4390–4395. doi: 10.1128/AAC.01487-06

TABLE 2.

Relationship between predictors of outcome and mortality at 28 days

Patient dataa No. of patient deaths/total n (%) P value OR 95% CI
Organism types
    E. coli 7/33 (21.2) 0.25b 0.6 0.2-1.5
    P. aeruginosa 18/46 (39.1) 0.10 1.8 0.9-3.7
    Enterobacter spp. 5/23 (21.7) 0.38 0.6 0.2-1.8
    Klebsiella spp. 7/23 (30.4) 0.92 1.05 0.4-2.7
    Proteus spp. 1/4 (25) 0.84 0.8 0.08-7.8
    Serratia spp. 5/21 (23.8) 0.54 0.7 0.3-2.1
    All others 2/7 (28.6) 0.95 0.95 0.2-5.1
    Polymicrobial 7/19 (36.8) 0.46 1.5 0.6-3.9
APACHE-II scores
    3-19 12/85 (14.1)
    20-24 10/38 (26.3) 0.11c 2.2 0.8-5.6
    25-29 12/22 (54.5) 0.0002 2.7 1.6-4.5
    30-53 12/16 (75) <0.0001 2.6 1.7-4.0
Sources of bacteremia
    CVC 1/14 (7.1) 0.09d 0.2 0.02-1.3
    UTI 5/26 (19.2) 0.22 0.5 0.2-1.5
    Pneumonia 13/34 (38.2) 0.22 1.6 0.8-3.6
    Other 2/9 (22.2) 0.62 0.7 0.1-3.3
    Unknown 31/93 (33.3) 0.24 1.5 0.8-2.8
Creatinine clearance rates
    >100 ml/min 4/28 (14.3)
    60-100 ml/min 7/41 (17.1) 0.76e 1.2 0.3-4.7
    <60 ml/min 21/57 (36.8) 0.039 3.5 1.1-11.5
    CVVHD 12/18 (66.7) 0.0007 12.0 2.8-50.8
    HD 7/30 (23.3) 0.28 2.1 0.6-7.9
Immune status
    Competent 16/60 (26.7)
    Compromised 36/116 (31) 0.55f 1.2 0.6-2.5
Ages
    ≤64 28/105 (26.7)
    ≥65 24/71 (33.8) 0.31g 1.4 0.7-2.7
Modes of therapy
    Monotherapy 21/73 (28.8)
    Combination therapy 31/102 (30.4) 0.82h 1.08 0.56-2.09
a

Abbreviations: CVC, central venous catheter; UTI, urinary tract infection; CVVHD, continuous venovenous hemodialysis; HD, hemodialysis.

b

P value compared to that of all other organisms.

c

P value compared to that of score range 3-19.

d

P value compared to that of all other sources.

e

P value compared to that of creatinine clearance of >100 ml/min.

f

P value compared to competent status.

g

P value compared to those aged ≤64.

h

P value compared to that of monotherapy.