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Proportion of mice harboring MXF-resistant mutants
| Drug regimen | Method of estimation | Proportion of mice harboring mutant strains on day:
|
||||
|---|---|---|---|---|---|---|
| 14 | 28 | 42 | 56 | 56 + 8 wka | ||
| 0.25% MXF | Direct | 0/3 | 1/3 | 1/2 | 1/19 | |
| Indirect | 0/3 | 1/3 | NAb | 3/19 | ||
| 1.5% MXF | Direct | 0/3 | 0/3 | 0/3 | 0/7 | 0/20 |
| Indirect | 0/3 | 0/3 | 0/3 | 0/7 | 0/20 | |
Mice sacrificed after being kept without treatment for an additional 8 weeks.
Not available due to overgrowth of contaminants.
