FIG. 1.

Distribution of translated BLAST (tBLASTx against nucleotide databases and BLASTx against protein databases) matches between all database “types.” The upper, largest circle represents matches to the env-nt and/or env-nr database comprised mostly of Sargasso Sea bacterial metagenomic data. The leftmost circle represents matches to either of the traditional GenBank (nt and nr) databases. The bottom right circle represents matches to any of a series of small viral metagenomes from terrestrial and marine environments (see Materials and Methods for details). Intersections of circles represent sequences that had BLAST homology to more than one database type, and the center area represents sequences with homology to all three types.