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. 2007 Oct 26;73(23):7753–7756. doi: 10.1128/AEM.01228-07

TABLE 4.

Differentiation of S. enterica subpopulations and serotypes by the tetracycline class of antibiotic compounds

Compound name Concn range of antibiotic (μg/ml) PM plate no. P of similarity to wt serotype Enteritidis PT13aa
BF serotype Enteritidis PT13a Serotype Enteritidis PT4 Serotype Typhimurium Serotype Heidelberg Serotype Newportb
Chlortetracycline 0.25-25 11C 0.063 0.739 0.528 0.723 0.000
Oxytetracycline 0.25-25 20B 0.149 0.514 0.406 0.276 0.000
Rolitetracycline 0.2-20 13B 0.216 0.831 0.694 0.475 0.000
Tetracycline 0.08-8 12B 0.556 0.297 0.780 0.081 0.000
a

A P of <0.01 indicates a significant difference.

b

Serotype Newport has multiple antibiotic resistances; thus, it has an origin of antibiotic resistance that is fundamentally different to that of serotype Enteritidis that correlates with single-nucleotide polymorphisms.