TABLE 1.
Salmonella genes induced during infection of pigs
| Category | Gene | Function | Tissue(s) |
|---|---|---|---|
| Adherence | wecC/rffG | UDP-N-acetyl-d-mannosaminuronic acid dehydrogenase/dTDP-glucose 4,6-dehydratase | Intestine and tonsil |
| bcfA | Fimbrial subunit | Intestine and tonsil | |
| fdx-hscA | Involved in assembly of Fe-S clusters | Intestine | |
| yciR | Putative diguanylate cyclase/phosphodiesterase | Intestine and tonsil | |
| Two-component regulator | hydH | Sensory kinase in two-component regulatory system with HydG | Intestine and tonsil |
| Aromatic hydroxylase | hpaB/hpaR | 4-Hydroxyphenylacetate catabolism | Intestine and tonsil |
| Virulence | metL | Aspartokinase II-homoserine dehydrogenase II | Intestine |
| Metabolism | cysQ | Sulfite biosynthetic protein | Intestine and tonsil |
| sppA | Protease IV | Intestine and tonsil | |
| cbiF/cbiG | Synthesis of vitamin B12 adenosyl cobalamide precursor | Tonsil | |
| Putative function | STM0611/0612/0613 | Putative hydrogenase protein | Intestine |
| oadB | Putative sodium ion pump | Tonsil | |
| rlgA | Putative integrase | Tonsil | |
| STM2689 | Pseudogene | Intestine | |
| STM1731 | Putative catalase | Intestine and tonsil | |
| STM2755/2756/2757 | Putative sugar phosphate aminotransferase/putative hexulose 6-phosphate synthase | Tonsil | |
| yiiG | Putative cytoplasmic protein | Intestine | |
| STM0325 | Putative IS3 transposase | Intestine | |
| STM4489 | Putative superfamily I DNA helicase | Intestine | |
| STM4320/pheR | Putative merR family bacterial regulatory protein | Intestine | |
| ybbP | Putative inner membrane protein | Intestine and tonsil | |
| STM1634/1635 | Putative amino acid ABC transporter permease component | Intestine and tonsil | |
| ybgH | Putative POT family transport protein | Intestine | |
| Reverse-oriented fusions | ygiK | Putative inner membrane protein | Intestine and tonsil |
| STM1368 | Putative Na+-dicaboxylate symporter | Intestine and tonsil | |
| yciA/yciB | Intracellular septation protein A/B | Intestine | |
| sitC | Fur-regulated Salmonella iron transporter | Intestine | |
| kduD | 2-Deoxy-d-gluconate 3-dehydrogenase | Intestine | |
| parA | Plasmid partition protein A | Intestine | |
| galP | Galactose/proton symporter | Intestine | |
| shdA | Fibronectin binding protein | Intestine | |
| Pslt068 | Putative ParB-like nuclease | Intestine | |
| napA | Periplasmic nitrate reductase | Intestine and tonsil | |
| hflK | FtsH modulator | Intestine and tonsil | |
| stbD | Putative fimbrial usher | Intestine and tonsil | |
| rpoN | DNA-directed RNA polymerase subunit N | Intestine and tonsil | |
| slt-trpR | Soluble lytic murein transglycosylase | Intestine and tonsil | |
| Pslt026 | Putative periplasmic protein | Intestine and tonsil | |
| wcaL | Putative glycosyl transferase | Tonsil |