Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 1999 Dec 13;147(6):1137–1144. doi: 10.1083/jcb.147.6.1137

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 1999 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

The αtub67C^P40mutation leads to elevated levels of achiasmate chromosome missegregation. The frequencies of X (dark bars) and 4^th (light bars) chromosome missegregation (nondisjunction) are displayed for various genotypes. The genotype at the αtub67C locus is represented as: +/+, two wild-type copies of the αtub67C gene; +/P40, heterozygous for the αtub67C^P40 mutation; and +/P40Δ, heterozygous for the αtub67C^P40 mutation. These experiments were done in both X/X and X/FM7 females, allowing us to examine segregation in oocytes with (+) or without (−) exchange on the X chromosome, respectively. N is the adjusted total of progeny scored (Hawley et al. 1993). Chromosome segregation was monitored by methods outlined in Hawley et al. 1993 and Sekelsky et al. 1999. Although females homozygous for αtub67C^P40are sterile, αtub67C^P40Δ/+ females are fully fertile and viable.