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NF-κB activation in CD14+ monocytes is equivalently enhanced following treatment with a natural or a synthetic TLR4 agonist. Monocytes were isolated and treated either with solvent-extracted LPS, which stimulates only TLR4, or with E6020. Levels of NF-κB activation were measured at 1 and 12 h following treatment. Activation of NF-κB is expressed in relative light units, presented as arithmetic means. Error bars, standard deviations.
