Skip to main content
. 2007 Sep 19;14(11):1483–1489. doi: 10.1128/CVI.00291-07

TABLE 6.

Adding a neutralizing antibody against IL-10 enhances the ESAT-6/CFP-10-driven IFN-γ release in most experimentally infected cattle

Animala IFN-γ release driven byb:
PBS Anti-IL-10 only ESAT-6/CFP-10 ESAT-6/CFP-10 + anti-IL-10
1 0.06 0.06 0.46 0.73
2 0.06 0.06 2.10 3.02
3 0.07 0.07 1.08 1.87
4 0.06 0.06 0.46 1.89
5 0.06 0.07 0.83 2.29
6 0.08 0.06 0.14 0.59
7 0.12 0.12 0.40 1.00
8 0.05 0.13 2.05 3.20
9 0.08 0.07 0.74 3.16
Uninfected animal Ac 0.06 0.06 0.06 0.06
Uninfected animal Bc 0.08 0.04 0.07 0.05
a

Animals 1 to 9 were infected with 5 × 103 CFU of M. bovis by the intratracheal route, and blood was sampled 15 weeks after infection.

b

Results are expressed in OD units for duplicate wells.

c

Uninfected cattle used as controls.